Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms.
Jackson et a, 2019.
Arterial thrombosis - insidious, unpredictable and deadly.
Jackson, 2011.
PI 3-Kinase p110β regulation of platelet integrin α(IIb)β3.
Jackson and Schoenwaelder, 2010.
Antiplatelet therapy: in search of the 'magic bullet'.
Jackson and Schoenwaelder, 2003.
Type I phosphoinositide 3-kinases: potential antithrombotic targets?
Jackson and Schoenwaelder, 2006.
An integrin α IIb β 3 intermediate affinity state mediates biomechanical platelet aggregation.
Chen et al, 2019.
Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets.
Ju et al, 2018.
Endogenous fibrinolysis facilitates clot retraction in vivo.
Samson et al, 2017.
Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces.
Schoenwaelder et al, 2010.
A shear gradient-dependent platelet aggregation mechanism drives thrombus formation.
Nesbitt et al, 2009.
Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin aIIbb3 adhesive function in platelets.
Schoenwaelder et al, 2007.
Importance of temporal flow gradients and integrin aIIbb3 mechanotransduction for shear activation of platelets.
Goncalves et al, 2005.
PI 3-kinase p110beta: a new target for antithrombotic therapy.
Jackson et al, 2005.
Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin a(IIb)b3.
Yap et al, 2002.
